MD – TISSUE

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INTRODUCTION

Compositions: Collagen, Ascorbic acid, Magnesium gluconate, Pyridoxine.

Dosage Form: Injectable Solution

Packaging: Box 10 vials ( single vial 2 ml – Extraction volumn)

Due to its special function, MD-TISSUE is also intended to limit the physiological deterioration of the skin and subcutaneous connective tissue, and counterbalance the effects of chrono-ageing and photo-ageing, such as:
• local anti-ageing treatment
• face and neck wrinkles
• firming of the subcutaneous and perivascular connective layer of
the face and neck
• alteration of the trophicity of the connective tissue of face and neck
induced by airborne pollutants / metabolic disorders.
MD-TISSUE is a medical device designed to help movement by counteracting the physiological aging of the connective tissue. Its main therapeutic functions include:
1. A barrier effect.
2. A lubricating action.
3. Mechanical support while administering other pharmacological
treatments.
MD-TISSUE is a medical device intended to be used by a qualified
staff in private or public health Facilities to:
➩ Act as a defensive barrier against free radicals.
➩ Counteract the physiological aging of the connective tissue.
➩ Soothe local pain caused by movement

Directions for use
Therapeutic protocol:
2 treatments weekly for the first 2 weeks, 1 treatment weekly until improvement of symptoms (average 8-10 sessions). It is possible to go on with 1 treatment every other week for 10 weeks at most.
For chronic pathologies: go on with 1 treatment weekly for 1 month until improvement of symptoms, then 1 treatment monthly.
Intradermal injection technique: the site of application must be aseptic;
Microinjections: insert the needle at 1-3 mm depth, and inject 0.2-0.3 ml into the affected tissue.
Tunnelling injection technique: inject 0.3 ml per wrinkle. Insert the needle beneath the skin the full length of the needle, cannulate the wrinkle by moving the needle gently to left and right, while injecting
the content of the syringe as the needle is withdrawn.
Periarticular injection technique: the site of application must be aseptic; insert the needle perpendicular to the skin surface at 2-4 mm depth, and perform microinjections of 0.3-0.5 ml.
Preparation for injection
For this purpose the use of the following materials and accessories is recommended:
• Materials for aseptic skin preparation: single-use gloves, iodine solution, alcohol solution, sterile gauze pads, ethyl chloride spray for the skin.
• Needles for microinjections: sterile 27 G, 4 mm.
• Needles for tunnelling injection technique: sterile 30 G, 13 mm.
• Syringes: 5 or 10 cc size, according to the volume of the solution to inject.

Contraindications / Side effects
There is no history of hypersensitivity to MD-TISSUE. However, patients with known hypersensitivity to any ingredient or excipient should be tested before use, making a spot injection into one arm and be monitored for 1 hour.
Warnings and precautions
A slight reddening at the injection site may be due to a mechanical effect of the needle or to a skin reaction. The application might cause symptoms of burning/pain at the injection site, that usually solve spontaneously within 5-10 minutes after the treatment.
Skin cleansing/disinfection is required before and after application.
Pyogenic bacteria may produce injection site abscesses.
KEEP OUT OF THE SIGHT AND REACH OF CHILDREN.
Do not use after the expiration date. The expiration date refers to approduct properly stored in its original and undamaged package. Use the product immediately after opening.
Instructions on use
MD-TISSUE may be used as a single treatment or mixed with other medical devices of the same range, in order to make a customised treatment according to clinical evolution.
Concerning its use for the treatment of face and neck wrinkles, and for
firming the subcutaneous connective tissue layer, MD-TISSUE should
preferably be associated with MD-MATRIX (e.g. MD-TISSUE 2 vials, MD-MATRIX 1 vial / treatment).
It may be used in patients who need a collagen supplementation or a topical antiaging treatment.
Instructions in case of damage to the sterile vials
Do not use if the seal is broken or if the vial is not perfectly sealed.
Once open, the content of the vial must be immediately injected. Do not use if the package is damaged

COMPOSITIONS

Collagen, Ascorbic acid, Magnesium gluconate, Pyridoxine.

USES

Due to its special function, MD-TISSUE is also intended to limit the physiological deterioration of the skin and subcutaneous connective tissue, and counterbalance the effects of chrono-ageing and photo-ageing, such as:
• local anti-ageing treatment
• face and neck wrinkles
• firming of the subcutaneous and perivascular connective layer of
the face and neck
• alteration of the trophicity of the connective tissue of face and neck
induced by airborne pollutants / metabolic disorders.
MD-TISSUE is a medical device designed to help movement by counteracting the physiological aging of the connective tissue. Its main therapeutic functions include:
1. A barrier effect.
2. A lubricating action.
3. Mechanical support while administering other pharmacological
treatments.
MD-TISSUE is a medical device intended to be used by a qualified
staff in private or public health Facilities to:
➩ Act as a defensive barrier against free radicals.
➩ Counteract the physiological aging of the connective tissue.
➩ Soothe local pain caused by movement